Projects top banner

Mathematical modeling of COVID-19 in 14.8 million individuals in Bahia, Brazil

Nature Communications

Article

COVID-19 is affecting healthcare resources worldwide, with lower and middle-income countries being particularly disadvantaged to mitigate the challenges imposed by the disease, including the availability of a sufficient number of infirmary/ICU hospital beds, ventilators, and medical supplies. Here, we use mathematical modelling to study the dynamics of COVID-19 in Bahia, a state in northeastern Brazil, considering the influences of asymptomatic/non-detected cases, hospitalizations, and mortality. The impacts of policies on the transmission rate were also examined. Our results underscore the difficulties in maintaining a fully operational health infrastructure amidst the pandemic. Lowering the transmission rate is paramount to this objective, but current local efforts, leading to a 36% decrease, remain insufficient to prevent systemic collapse at peak demand, which could be accomplished using periodic interventions. Non-detected cases contribute to a ∽55% increase in R0. Finally, we discuss our results in light of epidemiological data that became available after the initial analyses.

Juliane Oliveira

Daniel Jorge

Rafael Veiga

Moreno Rodrigues

Matheus Torquato

Nivea da Silva

Rosemeire Fiaccone

Luciana Cardim

Felipe Pereira

Caio de Castro

Aureliano Paiva

Alan Amad

Ernesto Lima

Diego Souza

Suani Pinho

Pablo Ramos

Roberto Andrade

Publication

Year of publication: 2021

Volume: 12

Section: 333

Date published: 12 January 2021

Identifiers

Alternative Titles

Preprint

File